Recent Posts

• June 24, 2020

  New publication

  We have a new publication in Cell Reports. We modeled 8,279 individual sample gene regulatory networks representing 29 tissues using PANDA and LIONESS. Using network analysis, we found that gene regulatory processes vary by sex across tissues and that many transcription factors have sex-biased targeting patterns. Differential gene expression between sexes is relatively modest on the non-sex chromosomes, generally occurring in tissues and pathways already known for...

• June 17, 2020

  New BioRχiv pre-print

  We have a new BioRχiv pre-print, which was work in collaboration with researchers from the University of Paris-Saclay, INRAE, CNRS. Maud Fagny modeled enhancer-driven regulatory networks for different maize tissues. This led to the discovery of tissue-specific regulatory modules involved in distinct functions related to the biology of each tissue, as well as the identification of transposable elements that have shaped the regulatory network in each...

• June 15, 2020

  New group member

  We are very excited to announce that Caroline Lunder Jensen has joined the lab for the summer. Caroline is a Master's student from the UiO:Life Science program and will be working on identification of regulatory subtypes in cutaneous melanoma.

• June 10, 2020

  PUMA accepted in Bioinformatics

  Our miRNA-target gene regulatory network reconstruction algorithm PUMA has been accepted for publication in Bioinformatics. We included an analysis on 38 tissues from GTEx to characterize tissue-specific regulation by miRNAs, identify miRNA functions, and their associations to disease. For more information, please see the publications and tools sections. The method is also available on NetZoo.

• June 09, 2020

  Scholarship for Ping-Han

  Many congratulations to Ping-Han, who received a scholarship from the Government Scholarships for Study Abroad from the Ministry of Education, Taiwan!